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Invitrogen
Peptide Histidine-Methionine Monoclonal Antibody (020-03)
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Product Details
ABS 020-03-02
Species Reactivity
Host/Isotype
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Type
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Immunogen
Conjugate
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Product Specific Information
ABS 020-03-02 detects PHM in human samples.
ABS 020-03-02 has been successfully used in ELISA procedures. PHM cross-reacts with PACAP (approximately 12%; incomplete, non-parallel inhibition).
NOTE: Concentration is lot-dependent and can vary from 0.85-1.15 mg/mL
Target Information
Human peptide histidine-methionine (PHM) is a 27-amino-acid peptide belonging to the glucagon-secretin family of peptide hormones. PHM is produced from the same prohormone as VIP, with which it shows considerable sequence homology. The VIP/PHM prohormone is produced by neurons in the central and peripheral nervous systems, often together with acetylcholine. In some situations the effect of the peptides is to reinforce and prolong the effects of neurotransmitter release. Like VIP, PHM is a vasodilator and stimulator of intestinal fluid secretion. High plasma levels of PHM are diagnostic of the corresponding peptide-producing tumor (VIPoma), associated with the watery diarrhea-hypokalemia-achlorhydria syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Bioinformatics
Protein Aliases: MGC13587; prepro-VIP; VIP peptides
Gene Aliases: PHM27; VIP
UniProt ID: (Human) P01282
Entrez Gene ID: (Human) 7432
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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